Synthesis of 2-acetamido-6-O-(5-acetamido-3,5-dideoxy-β-d-glycero-d-galacto-2-nonulopyranosylonic acid)-2-deoxy-d-glucose [2-acetamido-6-O-(N-acetyl-β-d-neuraminyl)-2-deoxy-d-glucose]
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منابع مشابه
Methyl 2-acetamido-2-deoxy-β-D-glucopyranoside dihydrate and methyl 2-formamido-2-deoxy-β-D-glucopyranoside.
Methyl 2-acetamido-2-deoxy-β-D-glucopyranoside (β-GlcNAcOCH(3)), (I), crystallizes from water as a dihydrate, C(9)H(17)NO(6)·H(2)O, containing two independent molecules [denoted (IA) and (IB)] in the asymmetric unit, whereas the crystal structure of methyl 2-formamido-2-deoxy-β-D-glucopyranoside (β-GlcNFmOCH(3)), (II), C(8)H(15)NO(6), also obtained from water, is devoid of solvent water molecul...
متن کامل2-Acetamido-2-deoxy-3-O-β-d-galactopyranosyl-d-glucose dihydrate
In the title compound, C(14)H(25)NO(11)·2H(2)O, the primary hydroxyl group connected to the anomeric C atom of the N-acetyl-β-d-glucopyran-ose residue exhibits positional disorder, with occupancy factors for the α and β anomers of 0.77 and 0.23, respectively. The two torsion angles (Φ and Ψ) and the bridge angle (τ) that describe conformation of the glycosidic linkage between the galactopyran-o...
متن کاملN,N'-Diacetylchitobionic N-alkylamides: synthesis, and interaction with two 2-acetamido-2-deoxy-D-glucose-binding lectins.
Condensation of N,N’-diacetylchitobiono-1,54actone, obtained by oxidation of N,N’-diacetylchitobiose, with n-alkylamines gave NJ’-diacetylchitobionic IValkylamides. The interaction of these glycolipids with wheat-germ agglutinin and Griffonia simplicifolia II lectin is described.
متن کاملFacile synthesis of nitrophenyl 2-acetamido-2-deoxy-α-D-mannopyranosides from ManNAc-oxazoline
The synthetic procedures for a large-scale preparation of o- and p-nitrophenyl 2-acetamido-2-deoxy-α-D-mannopyranoside are described. The synthetic pathway employs the glycosylation of phenol with ManNAc oxazoline, followed by nitration of the aromatic moiety yielding a separable mixture of the o- and p-nitrophenyl derivative in a 2:3 ratio.
متن کاملSynthesis and conformational analysis of 6-C-methyl-substituted 2-acetamido-2-deoxy-beta-D-glucopyranosyl mono- and disaccharides.
Several 6-C-substituted 2-acetamido-2-deoxy-beta-D-glucopyranosides (beta-D-GlcNAc monosaccharides 1a-3a and 1,4-linked disaccharides 1b-3b) were studied by solution NMR spectroscopy. Conformational analysis of the (6S)- and (6R)-C-methyl-substituted beta-d-GlcNAc monosaccharides indicates that the stereodefined methyl groups impose predictable conformational biases on the exocyclic C-5-C-6 bon...
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ژورنال
عنوان ژورنال: Carbohydrate Research
سال: 1982
ISSN: 0008-6215
DOI: 10.1016/s0008-6215(00)81851-0